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Systemic lupus erythematosus: one year in review 2026

Year: 2026

Type: article

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterised by a complex pathogenesis, heterogeneous clinical manifestations and a variable disease course. This review summarises the most relevant contributions on SLE published during 2025, following the framework of the One Year in Review series. In particular, we focus on emerging pathogenetic insights, novel and refined biomarkers, clinical manifestations and outcomes, comorbidities, and evidence from clinical trials and real-world studies, highlighting both recent progress and persistent unmet needs in the management of SLE.

Source: Clinical and Experimental Rheumatology

DOI: 10.55563/clinexprheumatol/mg0q41

Authors: Giancarlo Cascarano, Dina Zucchi, Chiara Cardelli, Marco Oliva, Giorgia Capozzo, Angela Elia, Ettore Silvagni, Elena Elefante, Alessandra Bortoluzzi, Chiara Tani

Institutions: University of Siena, University of Pisa, University of Ferrara, Arcispedale Sant'Anna

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7135083337

FWCI: 9.929

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Cited by: 2

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