Year: 2026
Type: article
Abstract: in routine clinical practice and is therefore typically inferred indirectly using advanced neuroimaging techniques. Cerebral microbleeds (CMBs), detected primarily with susceptibility-based MRI sequences, have emerged as putative imaging markers associated with axonal injury and injury severity in TBI. A broad and heterogeneous body of literature has explored their relevance using gradient-echo (GRE), susceptibility-weighted imaging (SWI), quantitative susceptibility mapping (QSM), and diffusion tensor imaging (DTI), as well as neuropsychological correlates. In this mini review, we provide a focused narrative synthesis of studies examining the detection, characterization, and interpretative framework of CMBs in TBI, with particular emphasis on susceptibility-based MRI and diffusion imaging approaches. We highlight areas of convergence and inconsistency in the literature and discuss methodological and conceptual considerations relevant to the use of CMBs as context-dependent imaging markers in TBI.
Source: Frontiers in Radiology
Authors: Dávid Bognár, Zalán Petneházy, Péter Laár, Petra Bondor, Tamás Dóczi, Bálint Környei, Arnold Tóth
Institution: University of Pecs
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,353
OpenAlex ID: W7135174807