Work

Bilateral Cardiac Sympathetic Denervation in Inherited Cardiac Arrhythmias

Year: 2026

Type: article

Abstract: ABSTRACT Background Bilateral cardiac sympathetic denervation (BCSD) is infrequently used for long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT), and its efficacy remains uncertain. Method We evaluated BCSD outcomes in these patients. Result Among three CPVT cases, none experienced preoperative syncope, fatal events, or appropriate ICD shocks after BCSD. In LQTS, syncope resolved in the LQT2/5 and LQT3 cases; the LQT3 patient with fetal‐onset ventricular fibrillation was discharged after mexiletine infusion, ICD implantation, and BCSD. Conclusion BCSD yielded meaningful only mild adverse effects in both CPVT and LQTS.

Source: Journal of Arrhythmia

DOI: 10.1002/joa3.70304

Authors: Hisaaki Aoki, Michiko Minegishi, Katsunori Okajima, Takashi Kumamoto, Daiji Takeuchi

Institutions: Osaka Women's and Children's Hospital, Maebashi Red Cross Hospital, Kakogawa City Hospital Organization, Saga University, Tokyo Women's Medical University

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,540