Work

Long-term sustainability and safety of a delivery-based early-onset sepsis evaluation strategy for very low birth weight infants

Year: 2026

Type: article

Abstract: Empiric antibiotics are given to about 80% of very low birth weight (VLBW) infants in the United States for concern of early-onset sepsis (EOS) [ 1 ]. We previously reported that implementing a delivery-based risk-stratification guideline for EOS evaluation among preterm infants in1 our level III neonatal intensive care unit (NICU), consistent with American Academy of Pediatrics (AAP) recommendations, was associated with reduced early antibiotic use without safety concerns [ 2 , 3 ].

Source: Journal of Perinatology

DOI: 10.1038/s41372-026-02607-y

Authors: Molly F. May, Alvaro Zevallos Barboza, Samuel J. Garber, Karen M. Puopolo, Sagori Mukhopadhyay, Dustin D. Flannery

Institutions: Children's Hospital of Philadelphia, University of Pennsylvania

Language: English

Topic: Neonatal and Maternal Infections

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,790