Work

Chirality Flipping: Engineering Lf SDR1 via Opposing Residue Substitutions to Expand the Substrate Scope for Chiral Alcohol Synthesis from Halogen-Substituted Acetophenone Derivatives

Year: 2026

Type: article

Source: The Journal of Organic Chemistry

DOI: 10.1021/acs.joc.5c02627

Authors: Yunye Wang, Di Wang, Jiuming Zhang, Yinan Li, Qingyu Wang, Bin Qin, Jingping Ouyang, Xian Jia, Song You

Institution: Shenyang Pharmaceutical University

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Department of Education of Liaoning Province, National Key Research and Development Program of China

Awards: G240220397, G4371550291, G88614138

OpenAlex ID: W7135222286

FWCI:

Cites: 33

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