Stem cell mitochondrial transfer rejuvenates CAR-NKT cell metabolism and antitumor activity
Year: 2026
Type: preprint
Source: Research Square
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: U.S. Department of Defense, California Institute for Regenerative Medicine, Parker Institute for Cancer Immunotherapy, National Institutes of Health, University of California, Los Angeles, Jonsson Comprehensive Cancer Center, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, California NanoSystems Institute, Congressionally Directed Medical Research Programs, DOD Peer Reviewed Cancer Research Program
Awards: Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy, G3595327501, G3785197112, Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy, G4705603570, HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma, Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer, G8023444137
OpenAlex ID: W7135244584