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Additional file 3: Figure S3. of αVβ3 Integrin regulates astrocyte reactivity

Year: 2017

Type: article

Abstract: β3 Integrin over expression permits Thy-1-induced signaling. A) Quantification of intracellular calcium levels in rat primary astrocytes transfected with pEGFP-β3 Integrin or pEGFP and stimulated with Thy-1-Fc. Trail-R2-Fc was used as a negative control. Cells were starved for 30 min. The arrow indicates the addition of Thy-1. B) Extracellular ATP measurement of primary astrocytes transfected with pEGFP-β3 Integrin or pEGFP, and treated with Trail-R2-Fc or Thy-1-Fc for 10 min. Cells were previously starved for 30 min. Values shown in the graph are the mean ± s.e.m. from three independent experiments. *p < 0.05. (PDF 174 kb)

Source: Figshare

DOI: 10.6084/m9.figshare.5457634

Authors: Lagos-Cabré, Raúl, Alvarez, Alvaro, Kong, Milene, Burgos-Bravo, Francesca, Cárdenas, Areli, Rojas-Mancilla, Edgardo, Pérez-Nuñez, Ramón, Herrera-Molina, Rodrigo, Rojas, Fabiola, Schneider, Pascal, Herrera-Marschitz, Mario, Quest, Andrew, van Zundert, Brigitte, Leyton, Lisette

Language: English

Topic: Cell Adhesion Molecules Research

Subfield: Immunology and Allergy

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7135369877

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