Work

Dilute Hyaluronic Acid for Lipoatrophy: Three Cases and Literature Review

Year: 2026

Type: article

Abstract: Localized lipoatrophy, characterized by subcutaneous fat loss, can result from trauma, injectable drugs, panniculitis, or idiopathic causes, leading to outcomes ranging from self-resolution to permanent disfigurement. This case series presents a novel approach using dilute hyaluronic acid (HA) for three cases of lipoatrophy (trauma-induced, radiation-induced, and steroid-induced), with all cases showing notable improvement after one session. This approach represents a promising, low-risk alternative for managing lipoatrophy of various etiologies, with potential benefits for patient quality of life.

Source: Cureus

DOI: 10.7759/cureus.105227

Authors: Juliana M O'Reilly, David S Kirwin, Travis Frantz, Willis Lyford

Institutions: Walter Reed National Military Medical Center, Naval Medical Center San Diego

Language: English

Topic: Facial Rejuvenation and Surgery Techniques

Subfield: Dermatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7135376325