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Acute myeloid leukemia with thrombocytosis: A paradox explained

Year: 2026

Type: article

Abstract: Acute myeloid leukemia (AML) with thrombocytosis is a rare entity, accounting for approximately 1% of AML cases. A 46-year-old male presented with fever and thrombocytosis, and was ultimately diagnosed with AML characterized by the recurrent genetic abnormality t(3;3)(q23;q23), associated with MECOM (EVI1) rearrangement. Despite induction chemotherapy, the disease course was aggressive with short-lived remissions and rapid progression. This case highlights the diagnostic challenges, prognostic implications, and therapeutic considerations of this rare AML subtype.

Source: Iraqi Journal of Hematology

DOI: 10.4103/ijh.ijh_148_25

Authors: Smita Gupte, Shweta Borkar, Poojal Devidas Mapari, Vaishnavi Mishra

Institution: Datta Meghe Institute of Higher Education and Research

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7135385292

FWCI:

Cites: 6

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