Work

Seeing through collagen: integrative pro-regenerative corneal implants for clearer future

Year: 2026

Type: article

Abstract: Collagen-based artificial corneas are a promising regenerative alternative to scarce donor tissue. However, their clinical success is limited by mechanical weakness, enzymatic degradation, and poor bio-integration. This review provides a comprehensive analysis of the current state and the future strategies to optimize collagen for making pro-regenerative corneal implants, enhancing the performance, functionality, and clinical viability of the collagen-based artificial cornea as a substitute for donor tissue.

Source: npj Regenerative Medicine

DOI: 10.1038/s41536-026-00471-0

Authors: Xia Huang, Mohammad M. Islam, Stephanie L. Watson, Hirak K. Patra

Institutions: Sichuan University, University College London, University of New Mexico, University of New Mexico Health Sciences Center, The University of Sydney

Language: English

Topic: Corneal Surgery and Treatments

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,190