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Sarcoid Uveitis with Choroidal Involvement

Year: 2026
Type: article
Study design: Observational Study
Abstract: Elli Joukainen,1,2 Jaakko A Antonen,1 Sanna Leinonen1,3 1Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; 2Eye Clinic, Lapland Central Hospital, Rovaniemi, Finland; 3Tays Eye Centre, Department of Ophthalmology, Tampere University Hospital, Tampere, FinlandCorrespondence: Sanna Leinonen, Tays Eye Centre, Tampere University Hospital, PO Box 2000, Tampere, FI-33521, Finland, Tel +358 3 311 611, Email [email protected]: To investigate characteristics of choroidal involvement in sarcoid uveitis.Patients and Methods: Included were patients with confirmed sarcoidosis and uveitis with an eye examination at the Tays Eye Center at Tampere University Hospital between January 2014 and January 2021.Results: Choroidal involvement was found in 31 of 97 sarcoid uveitis patients (32%), and 5 of them were detected only after reviewing the ocular images for this study. None of our patients presented with vasculitis. Choroidal nodules were found in 10%, multifocal choroiditis in 90% and serpiginous choroiditis in 3% of patients with choroidal involvement. They had a higher rate of chronic course of uveitis (71% vs 29%, p < 0.001), bilateral uveitis (90% vs 58%, p = 0.001), vitreal snowballs (65% vs 15%, p < 0.001), and macular edema (36% vs 9%, p = 0.001).Conclusion: Choroidal involvement is common and may be underdiagnosed in sarcoid uveitis. Therefore, we recommend carefully looking for choroidal involvement not only with slit-lamp but also with ocular imaging in patients with uveitis.Keywords: sarcoidosis, uveitis, sarcoid uveitis, choroidal involvement
Language: English
Subfield: Ophthalmology
Field: Medicine
Open Access status: green
OpenAlex ID: W7135726147
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