Additional file 9: Figure S6. of Olfactory coding from the periphery to higher brain centers in the Drosophila brain
Year: 2017
Type: article
Abstract: Sequence similarity of odorant receptors (ORs) is not the main factor to determine odor response similarity in the AL glomerular clusters. (a) Phylogenetic tree of D. melanogaster 60 ORs. The alignment data of the 60 ORs were obtained from the Database of Olfactory Receptors (DOR; http://caps.ncbs.res.in/DOR/index.html ), and the phylogenetic tree of the 60 ORs was calculated according to [75]. The percentages of replicate trees in which the associated ORs clustered together in the bootstrap test (1000 replicates) are shown next to the branches. Glomerular name is indicated after the OR name if it is identified in the established OR-glomerulus map [5]. Glomerular names are colored according to the three glomerular clusters detected in Fig. 4c. (b) A complete distance matrix measured with Euclidean distances for 25 OR sequence similarities. (c) Scatterplot of sequence distance versus anatomical glomerular distance for all 300 pairwise combinations of the 25 ORs and the 25 glomeruli. (d) Scatterplot of sequence distance versus PN response distance for all 300 pairwise combinations of the 25 ORs and the 25 glomeruli. Pairwise distance of PN response distance was calculated based on odor response of 25 PN classes using cosine distances for 17 odors. Multiple receptors co-expressed in the same OSN class and project to the same glomerulus (i.e., DL3 and DL4) have been excluded in these analyses (c, d). (PDF 842 kb)
Source: Figshare
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7136077528