Additional file 1: Figure S1. of Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol
Year: 2017
Type: article
Abstract: Neonatal alcohol effects on microglial opioid receptors and TLR4 pathway proteins in the mediobasal hypothalamus of male and female neonates. Showing protein quantification in isolated microglia from ad libitum (AD), pair-fed (PF), alcohol-fed (AF), alcohol-fed and naltrindole-treated (AF + NTD), and alcohol-fed and naltrexone-treated (AF + NTX) neonatal male and female rat pups at PND 6 by flow cytometry. Bar graphs show mean or median fluorescence intensity of staining of IBA-1 (A, B), MOR (C, D), DOR (E, F), TLR4 (G, H), p-38 MAPK (I, J), p-JNK (K, L), p-AKT (M, N), and NF-κB (O, P) from microglia isolated from each treatment group from male and female neonates. Data are represented as mean ± SEM (n = 3–7) and were compared by one-way analysis of variance (ANOVA) and the Newman-Keuls posttest. Differences between groups are shown by lines with p values on the top of bar graphs. (DOCX 964 kb)
Source: Figshare
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7136081553