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Additional file 8: Figure S4. of Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

Year: 2016

Type: article

Abstract: ATP-competitive mTOR inhibitors antagonize the effect of diverse classes of compounds in CAL-51. (A) Scatter plot of DSS scored for combinatory effect of different compounds along with dactolisib (Y-axis) on CAL-51 cell line compared to their single compound effect (X-axis). The right-hand plot represents the DSS computed using viability assay and the left plot represents cell death assay. Data points with DSS difference more than 10 are highlighted with different colors representing different classes of agents as listed in the color legend. (PDF 118 kb)

Source: Figshare

DOI: 10.6084/m9.figshare.4672939

Authors: Gautam, Prson, Karhinen, Leena, Szwajda, Agnieszka, Jha, Sawan Kumar, Yadav, Bhagwan, Aittokallio, Tero, Wennerberg, Krister

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7136069822

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