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Supplementary Figure S4 from Blocking Tryptophan Catabolism Reduces Triple-Negative Breast Cancer Invasive Capacity

Year: 2026

Type: supplementary-materials

Abstract: Compound AT-0174 decreased secreted KYN in TDO2 overexpression (OE) cells.

DOI: 10.1158/2767-9764.31762214

Authors: Li-Wei Kuo, Lyndsey S. Crump, Kathleen O’Neill, Michelle M. Williams, Jessica L. Christenson, Nicole S. Spoelstra, Micaela Kalani Roy, Amy Argabright, Julie A. Reisz, Angelo D’Alessandro, Meher P. Boorgula, Andrew Goodspeed, Mike Bickerdike, Benjamin G. Bitler, Jennifer K. Richer

Topic: Tryptophan and brain disorders

Subfield: Biological Psychiatry

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7136138398

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