Work

MOESM7 of The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements

Year: 2016

Type: article

Abstract: Additional file 7: Figure S5. Examples of BORIS binding at promoters trapped by SVA elements. The gene tracks represent cases of BORIS binding sites within genes’ promoters trapped by the indicated SVA element. The red double-headed arrows show the sequences trapped by SVAs and occupied by BORIS in K562 cells. BORIS ChIP-seq coverage and the CAGE tracks are shown for K562 cells. Expression from either minus or plus strands is shown by blue and red CAGE tracks, respectively. The particular examples are: BORIS binding site as the part of FDX1 promoter trapped by SVA-D, RHOT1 trapped by SVA-A, NDUFV2—by SVA-D, WRD33—SVA-F, PHKA1 and MMPE1—by SVA-D.

Source: Figshare

DOI: 10.6084/m9.figshare.4454921

Authors: Pugacheva, Elena, Teplyakov, Evgeny, Wu, Qiongfang, Li, Jingjing, Chen, Cheng, Meng, Chengcheng, Liu, Jian, Robinson, Susan, Loukinov, Dmitry, Boukaba, Abdelhalim, Hutchins, Andrew, Lobanenkov, Victor, Strunnikov, Alexander

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7136171059

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