Additional file 8: Figure S1. of The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine
Year: 2016
Type: article
Abstract: Mutational load predictions with different panel tests for the colon adenocarcinoma subset. Comparison of mutational load predictions using WES or either matched (a) or unmatched (b) large panel tests (n = 300 genes) demonstrates both can reliably predict the mutational load. The linear regression line is shown in black with 95 % confidence bands shaded in grey. The identity line (dashed) is shown for comparison. With medium sized panels (n = 48 genes), this ability decreases in both the matched and unmatched setting and is not possible with small (n = 15) gene panels. Note that hypermutated tumors were excluded from the regression analysis. (PDF 809 kb)
Source: Figshare
Authors: Garofalo, Andrea, Sholl, Lynette, Reardon, Brendan, Taylor-Weiner, Amaro, Amin-Mansour, Ali, Miao, Diana, Liu, David, Oliver, Nelly, MacConaill, Laura, Ducar, Matthew, Rojas-Rudilla, Vanesa, Giannakis, Marios, Ghazani, Arezou, Gray, Stacy, Janne, Pasi, Garber, Judy, Joffe, Steve, Lindeman, Neal, Wagle, Nikhil, Garraway, Levi, Van Allen, Eliezer
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7137002500
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