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Additional file 2: of ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1

Year: 2015
Type: article
Abstract: ERK1 and ERK2 protein expression in brain areas. (A-D) Brain areas were dissected as presented in Materials and Methods. Upper immunoblot: incubated with anti-ERK antibody, lower immunoblot: incubated with anti-phospho-ERK antibody. Positions of ERK1, ERK2, phospho-ERK1 (pERK1) and phospho-ERK2 (pERK2) are indicated on the sides. Brain parts are CE: cerebellum, CO: cortex, CR: cerebellum white matter center, PG: pituitary gland, ME: medulla, MS: mesencephalon, Mix: bottom of the brain in cranial box, OP: optic lobe, OL: olfactory bulb, PI: pineal gland, SC: spinal cord, TE: telencephalon. Control extracts from cultured cells, CCL39 from Chinese hamster (Cricetulus griseus) or NIH3T3 from mouse (Mus musculus); or from cattle medulla (Bos Taurus) are loaded on immuno-blots sides. (A) teleosts (European seabass, Dicentrarchus labrax, and African jewelfish, Hemichromis bimaculatus), and Bichir (Polypterus senegalus). (B) Amphibians: African clawed frogs (Xenopus laevi) and Axolotl (Ambiostoma mexicanum). (C) Birds: chicken (Gallus gallus) and Greater rhea (Rea americana). (D) Mammals: European rabbit (Oryctolagus cuniculus), cattle (Bos taurus) and the marsupial, Gray short-tailed opossum (Monodelphis Domestica). (PDF 2231 kb)
Source: Figshare
Language: English
Open Access status: green
OpenAlex ID: W7137086368
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