Additional file 2: of Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40
Year: 2016
Type: article
Abstract: Supplementary Methods and Results. Methods and results for the gene ontology over-representation analyses of top SNPs from the single variant analysis of CSF YKL-40 levels. 70 genes mapped to the top SNPs (p < 1 × 10-4) were significantly enriched in human brain and pituitary tissue at all levels of specificity. Figure illustrates the different human tissues with expression data available with Benjamini-Hochberg corrected p < 0.10 in the enrichment analysis and the Table shows the results for all tissues with uncorrected p < 0.05 in at least one specificity index. The specificity index represents how specific a set of genes are to a particular tissue. (DOCX 163 kb)
Source: Figshare
Authors: Deming, Yuetiva, Black, Kathleen, Carrell, David, Cai, Yefei, Del-Aguila, Jorge, Fernandez, Maria, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Huang, Kuan-lin, Sutphen, Courtney, Tarawneh, Rawan, Fagan, Anne, Holtzman, David, Morris, John, Goate, Alison, Dougherty, Joseph, Cruchaga, Carlos
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7137204002