Enteric and Sympathetic Nervous System Pathways Mediate Early Life Stress Effects on Gut Motility and Pain: Mechanistic Findings With Human Correlation
Year: 2026
Type: article
Source: Gastroenterology
Authors: Sarah A. Najjar, Helene Kildegaard, Ardesheer Talati, Priscila Dib Goncalves, Andrew Del Colle, Zixing Huang, Yan Tong, Daniel Juarez, Rahi Shah, Erfaneh Barati, Taeseon Woo, Melissa Medina, Narek Israelyan, Marguerite Bernard, Ruxandra Tonea, Michelle Ovchinsky, Noa Pesner, Roey Ringel, Luisa Valdetaro, Mette Bliddal, Martin Thomsen Ernst, Michael D. Gershon, Lin Y. Hung, Kara G. Margolis
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: MICROENVIRONMENT IN ENTERIC NEURON DEVELOPMENT, The role of mucosal serotonin in visceral nociception and gut motility, Linkage of s100a10 (p11) to enteric 5-HT4-mediated serotonergic signaling roles in GI motility, enteric nervous system development, and co-morbid dysfunction of gut and brain, Effects of prenatal maternal depression and antidepressant exposures on offspring neurodevelopmental trajectories: A birth cohort study, A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal Disorders, 9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGAN, 20/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT VCU, 3/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MINNESOTA, VZV in the enteric nervous system: pathogenesis and consequences, 4/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT FIU, 7/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT YALE, 17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLA, 15/21 ABCD-USA Consortium: Research Project Site at LIBR, 16/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UNIVERSITY OF ROCHESTER, 8/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT CHLA, ABCD-USA Consortium: Coordinating Center, 6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSU, 10/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT SRI, 12/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U PITTSBURGH, 19/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UVM, Impact of Gut Epithelial Serotonin on Afferent Neuron Function and Visceral Pain Signaling, 1/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U UTAH, 11/21 ABCD-USA Consortium: Research Project Site at UWM, Differentiating the roles and underlying mechanisms of serotonin in the gut epithelium and ENS to create a novel drug delivery system to treat disorders of gut-brain interaction and mood dysfunction, ABCD-USA Consortium: Data Analysis, Informatics and Resource Center, 21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTL, 13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSC, 5/21 ABCD-USA Consortium: Research Project Site at UC San Diego, 18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDA, 2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMB, Executive function and impulsivity as predictors of alcohol/cannabis co-use in adolescence: a longitudinal study, 14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
OpenAlex ID: W7137248088