Year: 2025
Type: article
Abstract: In the era of precision medicine, understanding how drugs interact with both the human body and the human genome has never been more vital. Pharmacokinetics and Pharmacogenetics – Principles, Applications, and Challenges explores this critical intersection, offering a comprehensive synthesis of the principles, methodologies, and innovations driving individualized drug therapy. This volume brings together leading research and applied perspectives that span from molecular mechanisms to population genomics. Through case studies and analytical advances, the book illustrates how pharmacokinetic modeling and pharmacogenetic profiling converge to optimize therapeutic outcomes, minimize adverse effects, and advance translational science. Topics range from blood–brain barrier dynamics and ocular drug delivery to validated bioanalytical methods, regional pharmacogenetic landscapes, and the emerging role of multi-omics in neuropsychiatric therapy. With its multidisciplinary approach and focus on integration, Pharmacokinetics and Pharmacogenetics – Principles, Applications, and Challenges is both a reference and a call to action - inspiring collaboration, innovation, and the continual evolution of pharmacology toward truly personalized medicine.
Author: Janko Samardzic
Institution: University of Belgrade
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7137760539