Work

342P Distinct TP53-associated co-mutation landscapes drive metastatic potential in non-small cell lung cancer

Year: 2026

Type: article

Abstract: Non–small cell lung cancer (NSCLC) remains a major cause of cancer mortality, with metastasis responsible for over 90% of deaths. Although TP53 is the most frequently mutated driver gene in NSCLC, its role in metastatic progression and its co-mutation patterns remain insufficiently characterized.

Source: ESMO Open

DOI: 10.1016/j.esmoop.2026.106654

Authors: J. Lu, B. Han, H. Zhong

Institutions: Shanghai Jiao Tong University, Shanghai Chest Hospital

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,910