Additional file 10: Figure S10. of Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
Year: 2016
Type: article
Abstract: Lipidomic analysis of DU145 tumour spheroids following SCD silencing. (a) Relative distribution of different free fatty acid (FFA) species in DU145 spheroids expressing either a control shRNA (shNTC) or a sequence targeting SCD (shSCD#2) cultured in the presence or absence of doxycycline for 9 days. (b) Relative distribution of different diacylglycerol (DG) species in spheroids before and after SCD silencing. Data represent the mean ÂąSEM of three biologically independent replicates. Statistical comparisons were performed using Student t-test (*pâ ¤0.05). (PDF 497 kb)
Source: Figshare
Authors: Peck, Barrie, Schug, Zachary, Zhang, Qifeng, Dankworth, Beatrice, Jones, Dylan, Smethurst, Elizabeth, Patel, Rachana, Mason, Susan, Jiang, Ming, Saunders, Rebecca, Howell, Michael, Mitter, Richard, Spencer-Dene, Bradley, Stamp, Gordon, McGarry, Lynn, James, Daniel, Shanks, Emma, Aboagye, Eric, Critchlow, Susan, Leung, Hing, Harris, Adrian, Wakelam, Michael, Gottlieb, Eyal, Schulze, Almut
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7138085877