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Additional file 2: Figure S2. of Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer

Year: 2016

Type: article

Abstract: Chronic treatment with gefitinib and PWT-458, alone or in combination, does not cause eight loss in mice. Mice bearing MDA-MB-468 xenograft tumors were treated with PWT-458 (100 mg/kg five imes/week), gefitinib (150 mg/kg five times/week), combination of both drugs, or vehicle control. The mouse body weight was measured in control and treated groups using a weighing scale. The results represent the mean body weight Âą S.E.M. (n = 5 mice per group). (PDF 880 kb)

Source: Figshare

DOI: 10.6084/m9.figshare.4352933

Authors: She, Qing-Bai, Gruvberger-Saal, Sofia, Maurer, Matthew, Chen, Yilun, Jumppanen, Mervi, Su, Tao, Dendy, Meaghan, Lau, Ying-Ka, Memeo, Lorenzo, Horlings, Hugo, van de Vijver, Marc, Isola, Jorma, Hibshoosh, Hanina, Rosen, Neal, Parsons, Ramon, Saal, Lao

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7138106610

FWCI:

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