Work

Does local bisphosphonate application or surface coating improve implant success? A systematic review

Year: 2026

Type: review

Abstract: The purpose of this systematic review was to evaluate the effectiveness of the local application and surface coating of dental implants with bisphosphonates in improving clinical outcomes. A comprehensive search was conducted across three electronic databases (PubMed/MEDLINE, Web of Science and Scopus) up to November 2025, following a PRISMA-based protocol. The major findings indicate that, despite some promising observations, current evidence does not conclusively support that local bisphosphonate use enhances osseointegration or decreases marginal bone loss. Overall, the available data remain insufficient to establish a clear clinical benefit. In conclusion, while bisphosphonate-enhanced implant surfaces represent a biologically appealing concept, further well-designed clinical trials are necessary to clarify whether these modifications effectively improve osseointegration and the quality and quantity of peri‑implant bone.

Source: Journal of Stomatology Oral and Maxillofacial Surgery

DOI: 10.1016/j.jormas.2026.102780

Authors: F. Pérez-González, L. Sánchez-Labrador, L.M. Sáez-Alcaide, C. López Carriches, C. Méniz-García

Institution: Universidad Complutense de Madrid

Language: English

Topic: Dental Implant Techniques and Outcomes

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,990