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Pharmacological and sensorimotor mechanisms linking obsessive–compulsive symptoms and cigarette smoking: A clinical laboratory study.

Year: 2026

Type: article

Abstract: < .001). Other OCS × VLNC or OCS × Nicotine interactions were nonsignificant. Findings from this study partially support a conceptualization that OCS-smoking comorbidity is explained by a hypersensitivity to some of smoking's nicotine-pharmacologic and sensorimotor-ritualistic negative reinforcing properties (i.e., urge and pain suppression). (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Source: Experimental and Clinical Psychopharmacology

DOI: 10.1037/pha0000843

Authors: Melissa K. Wong, Nikki S. Jafarzadeh, Gregory S. Chasson, Walter G. Dyer, Natalia Peraza, Reid C. Whaley, Marissa K. Anderson, David R. Strong, Mariel S. Bello, Raina D. Pang, Adam M. Leventhal

Institutions: University of Southern California, University of Chicago, Pennsylvania State University, University of California, San Francisco, University of California San Diego, Medical University of South Carolina

Language: English

Topic: Obsessive-Compulsive Spectrum Disorders

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Tobacco-Related Disease Research Program, National Institutes of Health, National Institute on Drug Abuse

Awards: The Impact of Social-Contextual Stressors on Psychopharmacological Mechanisms of Smoking Cessation and Relapse among Socioeconomically Disadvantaged Young Adults who Smoke Cigarettes, G7380055387, Expanding Capacity for Addiction Regulatory Science Research and Mentoring

OpenAlex ID: W7138282622

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