Year: 2026
Type: article
Study design: Observational Study
Abstract: direction of such changes in lung cancer patients are lacking.This study assesses lifestyle parameters and their associations with quality of life (QoL) in patients with newly diagnosed thoracic malignancies. Methods:A cross-sectional study at the University Hospital of Verona was carried out.Pts with recent thoracic cancer diagnoses completed a comprehensive survey evaluating: i) physical activity (Godin-Shephard Leisure-Time Exercise Questionnaire), ii) nutritional risk (NR) (NRS-2002), iii) sarcopenia risk (SARC-F), iv) cardiorespiratory fitness (FitMáx tool), and v) QoL (Functional Assessment of Cancer Therapy -Lung -FACT-L).Clinical data were extracted from medical records.Descriptive statistics and Pearson correlations were used.Results: A total of 96 pts (52 males; mean age 68.8; 67% current/former smokers) were enrolled.Most had non-small cell lung cancer (90%), and a metastatic-disease stage (65%).At diagnosis, 91% were physically inactive, 42% were at nutritional risk (NR), and 67% exhibited low cardiorespiratory fitness (CRF).Mean QoL scores of 55.5 ± 12,7 for FACT-TOI, 74.8 ± 18 for FACT-G, and 91 ± 19.8 for FACT-L.An inverse correlation was observed between BMI and NR (rs = -0.313,p = 0.003) and CRF (rs = -0.402,p<0.001).CRF showed a moderate correlation with both FACT-TOI (rs = 0.267, p = 0.029) and FACT-L (rs = 0.273, p = 0.025).SARC-F was inversely correlated with FACT-TOI (rs = -0.396,p = 0.002), FACT-G (rs = -0.299,p = 0.019), FACT-L (rs = -0.331,p = 0.009) and CRF (rs = -0.246,p=0.042).Higher levels of physical activity post-diagnosis were moderately associated with higher levels of prediagnosis physical activity (rs = 0.355, p < 0.001). Conclusions:In newly diagnosed thoracic cancer pts, physical inactivity, low cardiorespiratory fitness, and nutritional risk were common.Cardiorespiratory fitness and sarcopenia risk measures were associated with quality of life domains key.
Source: ESMO Open
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,910
OpenAlex ID: W7138378728
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