Work

284P Clinical validation of CCR2-targeted SPECT imaging as a biomarker for monocyte-macrophage infiltration and prognosis in non-small cell lung cancer

Year: 2026

Type: article

Abstract: The chemokine receptor CCR2 is pivotal in recruiting immunosuppressive monocytes and tumor-associated macrophages to the tumor microenvironment, influencing progression in non-small cell lung cancer (NSCLC). This study aimed to clinically validate CCR2 as a prognostic biomarker and develop a CCR2-targeted SPECT imaging probe for its non-invasive visualization.

Source: ESMO Open

DOI: 10.1016/j.esmoop.2026.106593

Authors: X. Li, P. Tang, Y. Ji, B. Hu, Y. Du

Institutions: Capital Medical University, Beijing Chao-Yang Hospital, Capital Medical University, Chinese PLA General Hospital

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,910