Work

A Dicer-Activatable Aptamer-Adamantane/siRNA (AptHyT-siRNA) Chimera Enables Synergistic Targeted Protein Degradation and mRNA Silencing

Year: 2026

Type: article

Source: Nano Letters

DOI: 10.1021/acs.nanolett.6c00010

Authors: Xiaoxing Chen, Qianqian Gao, Linlin Yang, Shan Mou, Ruowen Wang, Da Han

Institutions: Army Medical University, Shanghai Jiao Tong University, Renji Hospital, Xinqiao Hospital, Jiangmen Central Hospital, Binzhou Medical University, Chinese Academy of Sciences

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

Awards: G1008255959, G4250130617, G983549417

OpenAlex ID: W7138403448

FWCI: 1.939

Cites: 38

Cited by: 1

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