Additional file 6: Figure S6. of Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments
Year: 2016
Type: article
Abstract: Analysis of phosphatidylinositol species in DU145 cells following SCD inhibition. DU145 cells were treated with SCD inhibitors (100nM) or solvent (DMSO) for 48hrs in medium containing low serum. (a) Amounts of different PI species detected by LC-MS/MS. (b) Amounts of selected PI species. (c) Relative contribution of 40:6-PI to total PI pool. Data represent the mean ÂąSEM of three biologically independent replicates. Statistical comparisons were performed using Student t-test (*pâ ¤0.05). (PDF 512 kb)
Source: Figshare
Authors: Peck, Barrie, Schug, Zachary, Zhang, Qifeng, Dankworth, Beatrice, Jones, Dylan, Smethurst, Elizabeth, Patel, Rachana, Mason, Susan, Jiang, Ming, Saunders, Rebecca, Howell, Michael, Mitter, Richard, Spencer-Dene, Bradley, Stamp, Gordon, McGarry, Lynn, James, Daniel, Shanks, Emma, Aboagye, Eric, Critchlow, Susan, Leung, Hing, Harris, Adrian, Wakelam, Michael, Gottlieb, Eyal, Schulze, Almut
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7138482081