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Hematological Profiling and Biochemical Parameters Analysis in Female Breast Cancer

Year: 2026
Type: article
Study design: Observational Study
Abstract: Breast cancer is the most common cancer affecting women worldwide. It occurs when abnormal cells in the breast grow uncontrollably and form a tumor. Thirty-two serum specimens were taken from women and were divided into two groups: 15 samples from women with breast cancer and 17 from healthy women as a control group in Al-Amal Hospital for Oncology and Alnahreen center/Baghdad City, from the period March 2024 to December 2025. The results revealed that the breast cancer cases had a mean level of Hb of (12.73±0.18) compared to the healthy women (12.84±0.16) with no important variations, P=0.64. In addition, the mean levels of WBC count were (6905.26±448.33) compared to the controls (6881.76±412.34), P=0.96, and the PTL was (302.26±16.97) in comparison to the healthy females (298.23±19.03), P=0.87. Furthermore, the mean range of CRP in women with breast cancer was (2.07±0.32) compared to the control patients (1.03±0.16), with significant differences, P=0.006. While the mean range of CA15.3 was (60.45±23.50) compared to the healthy control (9.20±0.82), with an important difference, P=0.02. Moreover, the level of DHEA was elevated in breast cancer cases (278.68±33.40) in comparison to the control females, P ≤ 0.01. On the other hand, the range of CYP450 was (270.77±30.57) compared to the controls (52.84±13.35) with a highly significant differences P≤ 0.01.
Language: English
Subfield: Cancer Research
Open Access status: diamond
OpenAlex ID: W7138488330
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