Work

Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model

Year: 2026

Type: article

Source: Neuron

DOI: 10.1016/j.neuron.2026.02.004

Authors: Marc Dos Santos, Marc P. Forrest, Ewa Bomba-Warczak, Soumil Dey, Euan Parnell, Jessica M. Christiansen, Seby L. Edassery, Kun Yang, Lindsay N. Hayes, Jennifer M. Coughlin, Blair L. Eckman, Catherine R. Lammert, M. Dolores Martin-de-Saavedra, Maria V. Barbolina, Marco Martina, Akira Sawa, Jeffrey N. Savas, Peter Penzes

Institutions: Northwestern University, Johns Hopkins University, Johns Hopkins Medicine, University of Illinois Chicago

Language: English

Topic: Neuroscience and Neuropharmacology Research

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Brain and Behavior Research Foundation, National Institutes of Health, National Institute of Mental Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke

Awards: Synaptic and dendritic dysfunction in psychiatric disorders, Neuronal excitability and copy number variation disorders, NKCC1-KCC2 system modulation in rodent models relevant for psychiatric disorders, Nikon CSU W1 SoRa for the Center for Advanced Microscopy and Nikon Imaging Center at Northwestern University, Oklahoma COBRE in Structural Biology, Gene-Environment Interactions for Cortical Development and Schizophrenia, Oklahoma COBRE in Structural Biology, The Robert H. Lurie Comprehensive Cancer Center, Impact of the olfactory system on higher brain function and schizophrenia, High throughput marker for cognitive deficit: cellular autofluorescence

OpenAlex ID: W7138902121

FWCI: 4.698

Cites: 106

Cited by: 2

Related to: