Work

Influence of System Matrix Concentration and Frequency Selection on Reconstructed MPI Signals

Year: 2025

Type: article

Abstract: In Magnetic Particle Imaging (MPI), the system matrix (SM) characterizes the spatial encoding properties of the imaging system and the magnetic nanoparticle response. Ideally, for linear particle magnetization behavior, the concentration at which the SM is measured should not affect the reconstructed image. In this study, two SMs recorded with tracer concentrations of 8.5 mg(Fe)/ml and 1.92 mg(Fe)/ml were investigated. We show that, although the same SM is used, reconstruction discrepancies occur when the frequency coverage differs. We therefore propose to determine the usable frequency components based on the lower concentration SM to ensure a consistent reconstruction basis.

Source: International journal on magnetic particle imaging

DOI: 10.18416/ijmpi.2026.2603026

Authors: Jegatheeswaran, Sathurya, Meenen, Hanna, Gräfe, Ksenija, Buzug, Thorsten M.

Institutions: University of Lübeck, Fraunhofer-Einrichtung für Individualisierte Medizintechnik

Language: English

Topic: Characterization and Applications of Magnetic Nanoparticles

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: diamond

Funder: Damp Stiftung

OpenAlex ID: W7138941897

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