Human Microglia Engraftment in Mice
Year: 2026
Type: dataset
Abstract: This study investigates species-specific differences in CSF1R signaling to enable robust engraftment of human pluripotent stem cell-derived microglia (hMGs) into immunodeficient mouse brains without genetic modification. Flow cytometry was used to quantify hMG survival, engraftment efficiency, and maturation markers following PLX5622 treatment and transplantation.
Source: ImmPort
DOI: 10.21430/m3kx778cbb
Author: Wernig,Marius
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7139133043