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Diagnostic Value and Prognostic Significance of Laboratory Parameters in Adult COVID-19 Patients Admitted to the Intensive Care Unit by Age Group

Year: 2025

Type: article

Abstract: Aim: COVID-19 presents with heterogeneous clinical manifestations andlaboratory findings across different age groups. This study aimed to investigatethe diagnostic and prognostic value of laboratory parameters in adultpatients with COVID-19 admitted to the Intensive Care Unit, with particularemphasis on age groups.Materials and methods: This retrospective study included 283 PCRconfirmedCOVID-19 patients admitted to intensive care at AnkaraYenimahalle Training and Research Hospital between March 15 and June 15,2020. Patients were divided into four age groups: middle-aged (45–59 years,n=49), elderly (60–74 years, n=101), advanced elderly (75–89 years, n=122),and very elderly (≥90 years, n=11). Demographic data, clinical outcomes, andlaboratory parameters were collected and analysed. The predictive value oflaboratory parameters for mortality was assessed using ROC curve analysis.Results: Significant differences were observed in clinical outcomes acrossage groups, with the highest discharge rate in the 75–89 age group andlower rates in both the 45–59 and ≥90 age groups (p

Source: DergiPark (Istanbul University)

Authors: Genç, Murat, Bulut, Bensu, Akkan Öz, Medine, Gür, Ayşenur, Mutlu, Hüseyin, Yazıcı, Ramiz, Atik, Dilek, Yortanlı, Betül Çiğdem, Sarı, Eyüp, Yortanlı, Mehmet

Institutions: Ankara Eğitim ve Araştırma Hastanesi, Sağlık Bilimleri Üniversitesi, Gülhane Eğitim ve Araştırma Hastanesi, Aksaray University, İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi, Karamanoğlu Mehmetbey University, Konya City Hospital, Konya Numune Hastanesi

Language: English

Topic: COVID-19 Clinical Research Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7140007502

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