Interplay of pulmonary circulation, cardiac filling pressures, and sympathovagal balance in exercise-induced hyperventilation among cardiopulmonary disorders
Year: 2026
Type: article
Abstract: The results underscore a multifaceted interaction among cardiopulmonary hemodynamics, right heart pressures, ventilatory response, and autonomic regulation. In particular, altered RV-PA coupling correlated with heightened sympathetic drive, indicating that cardiopulmonary efficiency and hemodynamics may influence central autonomic outputs. This suggests that mechanical stress or overload in the right heart could modulate sympathovagal balance, thereby contributing to altered autonomic responses during exercise in patients with cardiopulmonary disorders.
Institutions: University of Milan, Aziende Socio Sanitaria Territoriale Rhodense, Universidade Federal Fluminense, University of Bergamo, Université Libre de Bruxelles, Aziende Socio Sanitarie Territoriale Ovest Milanese, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Mayo Clinic, Erasmus Hospital
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: G116144817, G4557397599
OpenAlex ID: W7140086806