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EVALUATION OF IMMUNOLOGICAL IMPACT OF PFASs EXPOSURE ON CYTOKINE RELEASE AND GENDER-BASED RESPONSES IN PBMCs

Year: 2026

Type: article

Abstract: Per- and Perfluoroalkyl substances (PFASs) are widespread synthetic compounds known for their environmental persistence and potential health effects. Due to their bioaccumulation and resistance to degradation, PFAS exposure has raised concerns regarding the interference with immune system functions. This study explores the immunomodulatory effects of 32 different PFASs on human peripheral blood mononuclear cells (PBMCs), with a focus on gender-specific differences in cytokine responses.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.19188302

Authors: Nunziangeli, Luisa, Condorelli, Giuseppe Emanuele

Institution: Polo d’Innovazione di Genomica

Language: English

Topic: Per- and polyfluoroalkyl substances research

Subfield: Environmental Chemistry

Field: Environmental Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: European Commission