Work

Percutaneous coronary intervention registries in the Asia-Pacific region: A systematic review of methodology and patient characteristics and meta-analysis of in-hospital mortality rate

Year: 2026

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: BACKGROUND: Percutaneous coronary intervention registries are pivotal for monitoring cardiovascular care. While several registries exist across the Asia-Pacific region, methodological diversity limits regional comparison. This systematic review aimed to summarize methodological characteristics, patient profiles, and in-hospital mortality rates in Asia-Pacific percutaneous coronary intervention registries. METHODS: A systematic literature search was conducted across MEDLINE, Embase, Scopus, Web of Science, and ProQuest Central, up to June 2025. Data on registry design, dataset characteristics, patient demographics, cardiovascular risk factors, procedural details, and in-hospital outcomes were extracted and synthesized qualitatively, with in-hospital mortality rates pooled using a random-effects model. RESULTS: A total of 27 studies encompassing 16 unique registries from nine countries were included. Despite targeting similar populations of patients with coronary artery disease undergoing intervention, marked heterogeneity existed in dataset structure, variable definitions, and data management approaches. Across all registries, men predominated, and hypertension and dyslipidemia were the most prevalent cardiovascular risk factors. The proportion of patients presenting with ST-elevation myocardial infarction ranged from 6.8% to 58.7%. In-hospital mortality rates ranged from 0.26% to 2.80%, with most registries reporting rates around 0.9-1.6%. CONCLUSIONS: The Asia-Pacific region would benefit from unified dataset standards to enhance data harmonization and comparability. While in-hospital mortality rates varied, they generally fell within international benchmarks, suggesting effective acute management. Further longitudinal data are needed to evaluate long-term outcomes and the broader impact of registry-based monitoring on enhancing quality in cardiovascular care.

Source: International Journal of Cardiology

DOI: 10.1016/j.ijcard.2026.134453