Work

Development of UM-200: A Novel Alkyne Amide-Based Inhibitor of the cGAS-STING Pathway

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00237

Authors: Leonard Barasa, Leo DeOrsey, Maeve D. O’Reilly, Shruti Choudhary, Sara E. Cahill, Anukriti Mathur, Akumalla Allabaji, Shreekrishna Nellikkalaya, Sourav Paul, Srinivasa Rao Vidadala, Sujit Kumar Sarkar, Muruganantham Rajendran, Santoshkumar N. Patil, Harikesh Kalonia, Jeffrey Hale, Fiachra Humphries, Katherine A. Fitzgerald, Paul R. Thompson

Institutions: University of Massachusetts Chan Medical School, Syngene International (India)

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Institute of General Medical Sciences

Award: G2597590110

OpenAlex ID: W7140135251

FWCI: 9.117

Cites: 62

Cited by: 4

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