Work

Direct RNA Triggering of Cas12a through the Native crRNA Architecture Enables Clinical Nucleic Acids Diagnostics

Year: 2026

Type: article

Source: Analytical Chemistry

DOI: 10.1021/acs.analchem.5c08220

Authors: Xuhua Zhao, Yunhua Wang, Leru Wang, Shuzhen Liao, Tao Gong, Mengyi Xiong, Baofeng Yu, Zhi-Ling Song

Institutions: Shanxi Medical University, Hunan Institute of Engineering, Hunan University, State Key Laboratory of Chemobiosensing and Chemometrics, Ministry of Education of the People's Republic of China, Qingdao University of Science and Technology

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, China Postdoctoral Science Foundation, Natural Science Foundation of Shanxi Province, Natural Science Foundation of Shandong Province, Science and Technology Program of Hunan Province

Awards: G273388855, G3791130843, G5708420379, G830051160, G8524744820

OpenAlex ID: W7140147575

FWCI: 5.526

Cites: 44

Cited by: 3

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