Work

INSL3 expression in Leydig cells is a biomarker for immunocastration in boars

Year: 2026

Type: article

Abstract: Background: Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives: It was hypothesized that the timing of gonadotropin-releasing hormone (GnRH) suppression by immunocastration differentially affects reproductive function, as reflected by testicular histology and expression of selected genes related to testicular function, steroid metabolism, and Leydig cell differentiation and function. Materials and Methods: Effects of three vaccination protocols on antibody titers, testicular histomorphology, and mRNA expression in immunocastrates slaughtered 4, 8, or 12 weeks (IC-4, IC-8, and IC-12, respectively

Source: Repository of the University of Ljubljana (University of Ljubljana)

Authors: Batorek Lukač, Nina, Škrlep, Martin, Poklukar Žnidaršič, Klavdija, Ferjan, Petra, Stefanski, Volker, Fazarinc, Gregor, Vrecl, Milka

Institutions: Agricultural institute of Slovenia, University of Ljubljana, University of Hohenheim

Language: English

Topic: Sperm and Testicular Function

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7140155163

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