Liver-Detargeted Aromatic Bioreducible mRNA Lipid Nanoparticles Confer Lymph Node Tropism and Robust Antigen-Specific Immunity
Year: 2026
Type: article
DOI: 10.1021/jacs.6c00080
Authors: Hannah M. Yamagata, Marshall S. Padilla, Alex G. Hamilton, Kelsey L. Swingle, Ajay S. Thatte, Adele S. Ricciardi, Anushka Agrawal, Emily Fitzgerald, Alexandre J. Poirier, Hannah C. Geisler, Ryann A. Joseph, Ori Z. Chalom, Sherry Du, Jacqueline J. Li, Dongyoon Kim, Ricardo C. Whitaker, Christian G. Figueroa-Espada, Emily L. Han, Amanda M. Murray, Mohamad-Gabriel Alameh, Drew Weissman, Michael J. Mitchell
Institutions: University of Pennsylvania, Abramson Cancer Center
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
Awards: G1977085870, G4667876998, Bone marrow vascular microenvironment combination RNAi-bortezomib nanotherapy for multiple myeloma, CAREER: Nanoparticle mRNA and DNA Immunoengineering of Macrophages for Solid Tumor Targeting, Engineering Biomaterials to Modulate the Bone Marrow Microenvironment in Multiple Myeloma
OpenAlex ID: W7140164901