Work

From colonisation to chronicity: adaptation of Mycobacterium abscessus in the cystic fibrosis lung environment

Year: 2026

Type: article

Abstract: Graphical abstract M. abscessus isolates change in phenotype over time of colonisation. Upper panel highlights the timelines between the early isolate and the later isolate in each pair. Lower panel highlights changes observed between isolate pairs. Changes marked with green arrows were shown by phenotypic assays and proteomic data while changes marked with pink text were identified from proteomic data only. Changes in biofilm formation, colony morphology and sliding motility were not seen in this data set but have been identified previously in clinical isolates.

Source: Microbiology

DOI: 10.1099/mic.0.001677

Authors: Niamh Duggan, Deirdre Keating, Joanna Drabinska, Ciarán J. Carey, Guerrino Macori, Kirsten Schaffer, Siobhán McClean

Institutions: University College Dublin, St. Vincent's University Hospital

Language: English

Topic: Mycobacterium research and diagnosis

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Irish Research Council for Science, Engineering and Technology