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Influence of spontaneous bursts of muscle sympathetic nerve activity on superficial femoral artery and femoral vein flow at rest and during slow deep breathing

Year: 2026

Type: article

Abstract: Sympathetic neurovascular transduction to mean arterial pressure (MAP), superficial femoral artery (SFA), and femoral vein (FV) flow were quantified at baseline and during slow deep breathing (SDB). MAP was unchanged during SDB, whereas MSNA was decreased, and sympathetic transduction to MAP, SFA flow, and FV flow (tendency) were increased. Respiratory-coupled oscillations in MSNA, SFA flow, and FV flow appear to work synergistically with the respiratory muscle pump to facilitate venous return during SDB.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00765.2025

Authors: Massimo Nardone, Kate N. Thomas, Jui-Lin Fan, Greer E. Pugh, James P. Fisher

Institutions: University Health Network, Toronto General Hospital Research Institute, University of Otago, University of Auckland

Language: English

Topic: Cardiovascular and exercise physiology

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Auckland Medical Research Foundation, National Heart Foundation of New Zealand