Work

Understanding Candidozyma (Candida) auris: genomic evolution, antifungal resistance and the growing challenges in global infection control

Year: 2026

Type: article

Abstract: exhibits remarkable persistence on human skin and inanimate surfaces, resistance to multiple antifungals, notably fluconazole, and biofilm formation, which hinders infection control and leads to hospital outbreaks with high mortality rates. Despite ongoing research, key aspects of its reservoir origin, transmission routes and the best way to combat its spread and multidrug resistance remain unclear. Improving genomic surveillance and antifungal strategies is crucial to contain its spread and mitigate the growing public health threat posed by this resilient and potentially fatal fungal pathogen.

Source: Journal of Medical Microbiology

DOI: 10.1099/jmm.0.002135

Authors: Karoline Kristina Kemmerich, Suélen Andreia Rossi, João Nóbrega de Almeida Júnior, Arnaldo Lopes Colombo, Lysangela Ronalte Alves

Institutions: Universidade Federal de São Paulo, Fundação Oswaldo Cruz

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico