The Oncogenic EGFR–SHC1 Fusion Confers Insensitivity to EGFR-TKIs via Dual Activation of N-EGFR Kinase Domain and C-SHC1 Phosphorylation Sites in Lung Cancer
Year: 2026
Type: article
Source: Cancer Discovery
Authors: Jiani Zheng, Shen Zhao, Jianhua Zhan, Weitao Zhuang, Maojian Chen, Wei Jiang, Yihua Huang, Junyi He, Liyang Hu, Lanlan Pang, Feng Hao, Jinhui Xue, Mengting Shi, Anlin Li, Jingxun Wu, Shaodong Hong, Yuanyuan Zhao, Feng Ye, Yan Huang, Hongyun Zhao, Yunpeng Yang, Wenfeng Fang, Li Zhang, Jing Li
Institutions: Fujian Medical University, Xiamen University, First Affiliated Hospital of Xiamen University, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Sun Yat-sen University, Sun Yat-sen Memorial Hospital, Guangxi Medical University, Tumor Hospital of Guangxi Medical University, Union Hospital, Fifth Affiliated Hospital of Sun Yat-sen University, Cancer Hospital of Shantou University Medical College
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W7140207705