Work

Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy in BRCA1/2 Mutation Carriers

Year: 2026

Type: article

Abstract: Objective: pathogenic variant carriers with MRI-only-detected breast lesions and compare these findings with those in non-carriers and assess lesion characteristics and diagnostic yield. Materials and Methods: carriers. Results: carriers and 28.6% for non-carriers. Conclusion: carriers. Prospective studies are needed to validate these findings and assess long-term clinical outcomes to inform personalized management approaches for high-risk populations.

Source: European Journal of Breast Health

DOI: 10.4274/ejbh.galenos.2025.2025-5-8

Authors: Aya Nagata, Mitsuhiro Tozaki, Kanae Taruno, Seigo Nakamura, Naoki Hayashi

Institutions: SHOWA Medical University, Sagara Hospital

Language: English

Topic: BRCA gene mutations in cancer

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7140225677