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Wcn26-6741 Immunomodulatory Effect of Double Plasma Molecular Absorption System in Patient With Acute-on-chronic Liver Failure

Year: 2026
Type: article
Abstract: The Double Plasma Molecular Adsorption Recirculating System (DPMAS) is an extracorporeal liver support system designed to remove albumin-bound toxins and inflammatory cytokines using dual adsorbent columns. In acute-on-chronic liver disease (ACLF), the surge of proinflammatory cytokines may lead to multiorgan failure and more liver injury. By removing these mediators, DPMAS may has an immunomodulating effect which reduce systemic inflammation and attenuate the severity of disease. We investigated the effect of DPMAS on clinical and inflammatory markers in patients with ACLF.
DOI: 10.1016/j.ekir.2026.105397
Authors: Tanat Lertussavavivat, Phatadon Sirivongrangson, Sombat Treeprasertsuk, Thaninee Prasoppokakorn, Prit Kusirisin, Anyarin Wannakittirat, Suri Tangchitthavorngul, Nuttha Lumlertgul, Sadudee Peerapornratana, Nattachai Srisawat
Language: English
Subfield: Hepatology
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,800
OpenAlex ID: W7140325147
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