Fibrin-Heparin–Coated Intracranial Stents as Salvage Therapy in Pediatric Focal Cerebral Arteriopathy–Inflammatory Type
Year: 2026
Type: article
Study design: Case Report
Abstract: Arterial ischemic stroke (AIS) in children is frequently associated with underlying arteriopathy. We report a 13-year-old male with progressive AIS due to focal cerebral arteriopathy of inflammatory type (FCA-i). Despite initial medical therapy—including antiplatelet agents, immunosuppressive therapy, antimicrobial treatment, and intra-arterial spasmolysis—he experienced clinical and radiographic deterioration. Endovascular therapy with balloon angioplasty and fibrin–heparin–coated intracranial stents achieved successful revascularization and stabilization. Vessel wall MRI and elevated Mycoplasma pneumoniae antibodies supported the diagnosis of FCA-i. Follow-up demonstrated sustained stent patency and vascular improvement, with persistent distal upper-extremity–predominant hemiparesis.
DOI: 10.3174/ajnr.a9317
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7140558663