Year: 2025
Type: article
Abstract: Theanine, which specifically accumulates in Camellia sinensis (L.) O. Kuntze, has demonstrated remarkable pharmaceutical and clinical benefits. Continuous investigations and related documents regarding theanine have been disclosed, and they are abundant and complex. Literatures disclosed in the most recent 5 years were indexed, and those focusing on the neuro-related functions of theanine and biosynthesis in the tea plant were selected and reviewed. Neuro-related pharmaceutical activities of theanine were present in treating with neural disorders, including sleep disorders, stress management, cognitive enhancement, reversal of neurol injury, and organ protection. Furthermore, the combination of theanine with other phytochemicals exerts a synergistic effect, which expands the applications of theanine. Meanwhile, the metabolism of theanine in tea plant was proposed. Genetic factors participating in the biosynthesis, transportation, and distribution of theanine were combed and illustrated. In addition, advantages of enzyme engineering and microbial engineering for the production of theanine were also summarised. A concise summary of the neuro-related benefits of theanine, as well as a systematic understanding of the accumulation of theanine in tea plant would be anticipated. Furthermore, clarification of the pharmacological mechanism, exploration of more novel pharmaceutical effects, and strategies to improve accumulation in tea products are awaiting elucidation. All share the objective of advancing the development and utilisation of theanine as a functional resource.
Authors: Qianting Luo, Xuelan Chong, Jianxin Zhang, Fan Huang, Anhui Gui, Jianan Wang, Hongxia Yin, Hua-Feng He
Language: English
Topic: Tea Polyphenols and Effects
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,638
Award: G4616668219
OpenAlex ID: W7140565571
FWCI:
Cites:
Cited by:
Related to: